I did take Creon, up to 3*4 per meal but as I improved, I find that Creon doesn't really add to comfort, so I reduced and stopped but keep in reserve. As I mentioned, I was on a clinical trial for a while that included a monoclonal. My friend had actually done research on a similar combo for Melanoma and they found that increasing Glycine in the diet helped greatly to reduce inflammation and actually destroyed melanoma cells. She recommended that I try to reduce my inflammation with bone broth....a great source of glycine. I make my own with either chicken backs or beef knuckle to render more glycine. I add onion, celery and carrot to my broth as it cooks to give more flavor. If the broth gels when it cools, I know it is high in glycogen. It is a great source of fluid and protein and soothing to sip. Try that as well. I also have some ginger chews as I find ginger helps to calm cramping and upset stomach. I will add things as I remember,,,,chemo brain wakes up during the day...ha.