Thank you so much for sharing your story. I'm not sure what I already told you that my Ki-67 was 2%. I asked my surgeon and oncologist to let me know my Ki-67 number. I tried to read about Ki-67 and everything I read was too scientific for me to understand. I do know that my surgeon said it was low and slow growing. I read the research and it did say that cancer patients with early breast cancer and a high recurrence (aggressive) plus other traits are a good candidate. I wrote in my portal and asked my doctor if I had a Oncotype DX score and if I didn't could I get one. I never heard of it before until I researched it. The only traits I see myself having is that I'm early breast cancer (Stage IIIa) with HR pos and HER neg. I read that early breast cancer is Stage I to stage IIIA. The research listed those requirements plus additional traits including the Ki-67 number. If mine is low, then I'm assuming I shouldn't take it. Please if you don't mind sharing, could you tell me what you learn? I agree that if your team says you're a good fit then you should try it. I'm looking to do the same. You are so lucky to be with Mayo. They are the best! I just need more information and match it with the research. My concern with this drug is that 5,600 people is not that much and 17% dropped out. The lung clots and inflammation as I have a lung disease is very scary. At the beginning, I told my doctor to do whatever it takes to make me live longer and I also said I didn't want to know all the information. But this drug seems too new. Since I don't really know much about my cancer I need more information to make an informed decision. When I went into his office I thought I would only being taking the anastrozole and then he wanted to add this drug. Again, I'm so glad I joined this group. I so appreciate all the people that are replying to my concerns.