I’ve had insomnia long before I was on an AI. I take a low dose ambien every night and sleep great. 3-4 days after my last dose of anastrozole, I couldn’t sleep all night (even with low dose ambien!) - happened again the next night. I texted my onco’s nurse and she told me to up my dose of ambien for a bit until the AI gets out of my system. Tried it last night and slept great! I read that it takes 6-12 days for it to get out of my system! Has anyone heard of this before?