I too was diagnosed with PMF in my 40s at 47; though that is truly the confirmation date as I have had mild symptoms for years. The date of confirmation is almost 2 years from my stage 3 melanoma diagnosis. My enlarged spleen was found during a post immunotherapy treatment CT scan (previously stated this was US, but went back to verify) by chance. The CT was to verify no spread of melanoma to the chest (discovered in my neck), but the CT went far enough to see a portion of enlarged spleen. Originally Dr. was not concerned, however my dad was in the last stages of MF and I knew the enlarged spleen was a known symptom. I pushed for more testing and I now have a new oncologist!
Bone marrow biopsy confirmation last week shows some fibrosis, but blood numbers other than platelets are normal. My spleen has shrunk dramatically in 10 weeks (around 40% decrease).... some dietary changes, some lifestyle changes, but no meds nor vitamins other than Vit D.
Meet with Dr. tomorrow, will discuss some of stimme and onamission's liposomal mixes that give me hope for continued stability as I would like to stay away from the drugs as long as possible.