I have MDS with ring seidoblast I took Procrit for 4 years then went to Inqovi with poor results. Finally I went to MD Anderson Houston Texas to Dr Garcia Mareno. He told me that there were many strains of MDS and would need a nother biopsy of my bone marrow to determine for sure what would help me. After 15 days he started me on Luspatercept that was last December I have been transfusion free with a red blood cell count of 10 plus. MD Anderson was the only cancer institution that I had gone through that throughly went to diagnose what strain of MDS I have. I do not build adequate red blood cells. I feel pretty good still fatigued but I am still anemic at 10. But I am transfusion free with little or no side effects.