Hi, @barbiep Welcome to Connect.

I have been on Tymlos since March. Initially I had some slight light-headedness the following morning (I take it before bed at night) but that has passed. The only other side-effect that I can definitely say is from Tymlos is what people refer to as "puffy belly" which is actually fluid retention. It's a nuisance but I can live with that.

Some people start out with a lower dose but my endocrinologist said to start out with the full dose. Then if you do have a problem you can go to a lower dose and build up.

The only downside I see to Tymlos is the cost. I am on Medicare and so there is no assistance. Many people who are not on Medicare are able to get it at a greatly reduced cost and some even get it free!

This is the first drug I have been on for osteoporosis. I had a minor hip fracture in July 2019 which led to a DEXA. I had not had a DEXA for five years and my previous one showed osteopenia so I believe I should have. If you have a fracture that can make a difference in whether these expensive injectables are approved by your insurance or Medicare, even without having had another drug first.
JK