Hello @contentandwell 😊 I hope all is well with you! What is interesting to me is you had a liver transplant and the medication gave you elevated creatinine levels (kidney). I had a kidney transplant and the medication is giving me elevated liver levels. My medication was lowered and my liver numbers improved, but are still slightly elevated so I am going for a liver ultrasound next week. It sounds like they ended up changing you from Tac to sirolimus to protect your kidneys. I think my liver enzymes may be the Cellcept instead of the Tac, but I am only guessing. Do you know why they stopped your Cellcept? Is that what normally happens with liver transplant or did you have a special circumstance that stopped your Cellcept? Thank you so much JK!