Mary - Fatigue is listed as one of the side effects of Esbriet, but I am not sure that it should be this severe early on. Also, as a diabetic, he undoubtedly take a number of other medications, some of which may be interacting with the new one. Also, were his kidney and liver functions tested before starting the new med?
If I were in your situation, my first call would be to the doctor, asking for a full evaluation of all the medications he is taking and their potential interactions. If that does not leave you feeling comfortable, maybe your pharmacist can help - often they are experts at figuring out where tie conflict is. Finally, every time my husband (who does not have PF) gets a new med or has one taken away, who diabetes meds generally need adjustment.
Let me know what you find out.
Sue