Tymlos and family history of cancer?

Posted by monak @monak, Oct 25, 2021

I’ve been reading these helpful posts and may have made my first post in the wrong spot, so I’m posting again. I’ve just started taking Tymlos, and I’m worried about the warning about rats getting cancer. My sister has had breast cancer, and my dad died from cancer. Do you think me taking Tymlos is too risky? Would a family’s genetics affect a decision to be on Tymlos, I wonder?

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As I wrote before, I myself HAD breast cancer and conceivably could still have it growing somewhere in my body, including bones. That has to do with metastasis, the spread of an original cancer to other places. So a few months ago I asked if this was a concern.

If you have a family history, and then get breast cancer while on Tymlos, you would probably get cancer only in your breast, not your bones. It isn't even relevant.

As I wrote elsewhere, the rats in the study had huge doses for a long time. I believe Forteo's black box warning was recently removed and so was the time limit- because NOONE got bone cancer from it. Tymlos is very similar. The black box warning will probably be removed from that too but it is newer than Forteo and a certain amount of time needs to go by before the time limit is removed and the black box warning as well.

This is not a realistic worry, based on family history. As a cancer patient, I am not worried nor are my doctors.

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@windyshores

As I wrote before, I myself HAD breast cancer and conceivably could still have it growing somewhere in my body, including bones. That has to do with metastasis, the spread of an original cancer to other places. So a few months ago I asked if this was a concern.

If you have a family history, and then get breast cancer while on Tymlos, you would probably get cancer only in your breast, not your bones. It isn't even relevant.

As I wrote elsewhere, the rats in the study had huge doses for a long time. I believe Forteo's black box warning was recently removed and so was the time limit- because NOONE got bone cancer from it. Tymlos is very similar. The black box warning will probably be removed from that too but it is newer than Forteo and a certain amount of time needs to go by before the time limit is removed and the black box warning as well.

This is not a realistic worry, based on family history. As a cancer patient, I am not worried nor are my doctors.

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Thank you for continuing to explain. You’ve made me feel better.

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@monak

Thank you for continuing to explain. You’ve made me feel better.

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Tymlos is very helpful. Osteoporosis is a serious condition. Believe me, I have had cancer and I have had fractures, both. Fractures are so painful and disabling. Evidence is overwhelming that you are not at risk of bone cancer taking these meds for the prescribed time.

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I have severe osteoporosis and was told by my doctor to try the injections Tymlos or Forteo. I am still doing my research before I decide which one to take. I am 67 petit and small framed women. I have family history of cancer my oldest sister died of pancreatic cancer and just lost a younger brother from stage 4 lung cancer. Reading your comments is helping me and taking injections on daily basis for two years a bit scary. How does it feel??

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@kebena the needles are small and you inject in tummy fat. For me it was like brushing my teeth. No big deal. I didn't feel anything!

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@kebena

I have severe osteoporosis and was told by my doctor to try the injections Tymlos or Forteo. I am still doing my research before I decide which one to take. I am 67 petit and small framed women. I have family history of cancer my oldest sister died of pancreatic cancer and just lost a younger brother from stage 4 lung cancer. Reading your comments is helping me and taking injections on daily basis for two years a bit scary. How does it feel??

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Good morning…I have been on Tymlos since June of 22 and the injections are easy and pretty much pain free. The needles are very small. I squeeze the fat on my lower abdomen, insert the needle and then let go of the fat and inject. It’s very easy. By the way, I’ve had an 11% gain in my spine. It’s been worth it. I too am small framed, and my mother passed of ovarian cancer in 1985. The black box warning of bone cancer in rats came from rats receiving very high doses of Tymlos…no women have been diagnosed after receiving Tymlos. Wishing you a successful journey. Rose 🌹

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