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Side Effects: Amiodarone vs Sotalol

Heart Rhythm Conditions | Last Active: Aug 7, 2023 | Replies (24)

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@amandaa

@aharders Hi there and welcome to Mayo Clinic Connect.

According to the NIH, There is no significant difference between amiodarone and sotalol in converting atrial fibrillation to sinus rhythm. However, amiodarone is more effective in maintenance of sinus rhythm than sotalol. The adverse reaction of amiodarone on heart is less severe than that of sotalol. https://pubmed.ncbi.nlm.nih.gov/16620720/

Here is a study that the New England Journal of Medicine did where they compared the two.
https://www.nejm.org/doi/full/10.1056/NEJMoa041705

@lucky1038, @ashby1947 and @danab has taken one or both. I would like to invite them to the conversation to weigh in.

Which medicine are you currently taking and do you have a-fib?

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Replies to "@aharders Hi there and welcome to Mayo Clinic Connect. According to the NIH, There is no..."

Sotalol and only one (very brief) episode since taking it.