I met with new oncologist/hema this week. I will be getting a bone marrow biopsy, as expected, to determine the amount of fibrosis. Dr. was a bit optimistic that my CBC was not presenting evidence of MF. Other than a slightly elevated platelet count they are fairly stable and within margins each test. The enlarged spleen does not signify MF by itself. The JAK2 mutation is not hereditary, but the cause of it may be, not enough data on the subject to know what causes the mutation. It appears that this was caught early and potentially prior to the MPN presenting. Will know more after the biopsy. Be well.