I, too, have been having SOB, sometimes severe which I had blamed on an injection of Prolia. I saw my Internist this morning - he does not think it's the Prolia. I told him I have an appt. with my cardiologist's PA and am hoping she recommends a cardiac cath to check for a coronary artery blockage. I've had 3 stents placed, each of them 4 years apart - it has now been 9 years since my last cath and I would be curious as to whether I need additional stent(s). i hope you find the source of your problem. You mention no problems with your heart or lungs, but have you had a stress test and/or cardiac cath - might be a good idea.