Husband is on clinical trial in Rochester so we are there each week. I have a spreadsheet that I haven't updated since June with a lot of expenses -- and we have great insurance. We have been had a situation where the chemo treatment was rejected, bills that show up that are in error for thousands of dollars, and mountains and mountains of paperwork and expenses. Plus staying employed is a challenge to pay for it. I'm still working but my husband had to retire. The stress of stage 4 cancer is one thing but adding to it with a significant financial burden and working with not so friendly insurance companies makes it unbearable. Glad you are doing this study.