I have working the pain caused by my demyelinating peripheral neuropathy for years. I am in pretty good shape now, pain wise. Combination of: Gabapentin 4000mg four times per day. Yes I get up between 2 and 3 AM to take one, but the dogs have fallen into that routine. Amitripyline, 25mg prior ro bed. One each night if I have exercised that day (swimming). Otherwise two tabs. Neurologist prescribed 1 to 2 tabs for pain and sleeping. IVIG once per month for two consecutive days -for pain and slow the disease down. Neurostimulator, primarily for spine pain (all L's fused and 5 C's), but it allowed me to decrease pain medication. Yes, I was taking more, but neurostimulator cut my gabapentin from 3200gm per day to the 1600mg. I had the cattle prod to the feet at night, but the neurostimulator seems to make that a thing of the past. Lot of other good advice on this blog - just try them out to tailor to your needs. I tried Gralise, a time release version of gabapentin, but it did not work. Tried Lyrica - terrible side effects. I can live with the combination I have now and even have some growth potential with the gabapentin.