Thank you too. I’ve tried it all even combo drug with linzess, the prescription combo drug with amitiza and with trulance. Absolutely nothing. My problem is it gets stuck way in my colon not down in sigmoid or below area so suppositories and enemas don’t work. When I take Philips in order for it to work I take 3 capfuls of liquid and three Philips in the pill form. If my morning nothing happening my Gastro has me fast and I do a prescription from pharmacy that you get as your prep for a colonoscopy. Mine is that severe. I have backup prescriptions at home you use for colon prep. I have an extremely lazy colon. I get pelvic floor PT weekly and acupuncture twice a week and nothing. The surgery scary because if they remove my entire colon and I’m still constipated they can try drugs to help but if they don’t work then I’d need a bag possibly three months later. It’s a tough decision. I just always pray on this site someplace someone just might come up with something that will work. I appreciate all the help from everyone.thanks, Joanne