Prunelax is nothing like dulcolax, it is mild in comparison. No cramping! I take at bedtime and I usually wake up around 6am and do once, 15 minutes later again, and a third time a little later. It's the only thing that empties me other than a colonoscopy prep. And, it's not diarrhea, its more like mud. I've tried it all, and it works for me and I was hesitant at first. Keep battling!