Hi @pacarolyn, You will notice we modified the title of your discussion to better describe the question you are asking and to hopefully allow more members with experience to join the conversation. My PMR is in remission. I have always had discomfort when sitting for too long. I wouldn't really call it pain but a little more like an ache. I have had elevated LDL numbers but the doctor or rheumatologist never mentioned it being related to PMR. You may be interested in an older discussion on Connect that talks about the pain.

Pain in the butt - Can't sit down: https://connect.mayoclinic.org/discussion/pain-in-the-butt-cant-sit-down/

Have you discussed it with your rheumatologist or doctor to see what they think?