Hello Marylynda...I too have ET and have fatigue. Like you, the fatigue used to be extreme but I have been on Hydrea for three years having it increased recently and slowly the fatigue lessened and my energy increased slightly. It takes time for the hydrea to catch up with the disease. My best advice is to do what you need to do in the morning and save the afternoon for resting.
I think we will always have fatigue so we have to really take care of yourselves. That is all I can say for now.....hope this helps....Claire