@kateia - I was also diagnosed Type 2 diabetic and took Jenuvia for a couple of years. My father had CAD and diabetes, high cholesterol.
I was overweight and decided to lose weight- I lost 45 lbs and I did not need to take the pills. Just diet controlled. Blood sugar and HgbA1C are close to normal.
I don’t think there is a safe time specifically when you have to worry about the accompanying illnesses.
I do know that I already have coronary calcifications- and I have always tried my best with diet and exercise, which made me upset in a way. It’s genetic and current treatments are there to delay and prevent problems.