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Transplant: No or Few Antibodies after COVID Vaccination

Transplants | Last Active: Mar 7, 2022 | Replies (193)

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@leahdrose

Hi! I was diagnosed with IgA Nephropathy almost 20 years ago. I followed strict diet, almost vegetarian and was cautious with sodium, potassium, phosphorus and protein intake. Although, fruits and vegetables are generally good for the body, some of them are high in potassium. Knowing what you can and cannot eat is very important. My friends and family suggested that I eat this and take that, they’re good for you, but with kidney disease, it’s different. There’s a lot of dietary restrictions.
I was blessed with kidney transplant 4 months ago. My body is still adjusting to immunosuppressant medications. My doctor recommended that I get the third vaccine 8 months after my second dose, which will be in November. I’ve read several articles the transplant recipients develop zero or low antibodies to protect from Covid. For the time being, I’m staying safe at home.

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Replies to "Hi! I was diagnosed with IgA Nephropathy almost 20 years ago. I followed strict diet, almost..."

@leahdrose Congratulations on your recent transplant! And, welcome to Mayo Clinic Connect. I am Stage 4 [almost Stage 5] kidney disease, and have had 3 doses of vaccine. My husband is a kidney recipient and also has had 3 doses of Pfizer vaccine. Your body has a lot to get used to now, with new medications and the adjustments that come along with them. How are you feeling? Will you get tested for antibody levels after your third dose in November?
Ginger

@leahdrose, Welcome to Mayo Clinic Connect. Twenty years sounds like a long time ago. In fact aroujnd 20 years ago is when I was diagnosed with my liver disease (PSC) that was progressive and without a cure. I can really understand how you must have felt with all of the 'helpful' suggestions from family and friends. I had the same experience with advise from well-meaning friends.
You are absolutely correct that your body is still adjusting to the immunosuppressant medications, along with continued healing and gaining of strength. It sounds like you have a good relationship with your doctor who is leading your Covid19 vaccination schedule.
Are you comfortable with getting outside and getting some exercise? Now that, I presume, you are feeling better, what are you doing with your time while being safe at home?

I always love how friends give such helpful advice, here are a few of my favorites: there are yoga poses that will correct kidney failure, this supplement improves kidney health, try drinking more water. I know they mean well, but I think I’ll just listen to my Mayo transplant team. My favorite these days are all the people who say don’t worry, I’m vaccinated and very careful. Really? I just saw picture on Facebook of you at an indoor concert, jam packed with no mask on! I’ll just keep to myself, thanks.
By the way, I lost a lot of hair for about a year after my transplant, but eventually it all came back. Wish I’d known about Biotin!

Congratulations on your transplant! I am 4 years out and had my third dose of Moderna as soon as I was allowed.No antibodies on first two but I did have the spike protein test for antibodies and did have a result of >250. While that is of some comfort, we don't know what that means or what protection it affords someone on immunosuppressants. Flu shot will come next week.I have worn a mask at the beginning of flu season and gotten a flu shot every year. I wore a mask in crowded environments. I haven't been ill in 4 years. My entire family is vaccinated with the exception of the 3 small grandchildren. We all wear masks, social distance, wash hands and follow safety protocol. We will continue to do so in order to protect the special gifts I have been given. You are wise to stay home. You have good instincts. When in doubt, talk to your team.