I am so sorry you're going through this Anne... I went through it with my sisters years back. We grew up very close and they were older than me so I always looked up to them. They reacted negatively to some decisions I made in my life and didn't speak to me for 10 years. It was horrible and painful and I grieved every day. I know from having grown kids now how painful your situation is. Just don't give up. I sent my sisters cards for every birthday, Christmas, etc. I reminded them that I loved them and would always be right there when they were ready to talk. I wanted to give up when years of cards and letters went unanswered but my wife kept encouraging me to keep trying. Eventually they did come around and we healed and thankfully, had 5 years of being closer than ever and talking on the phone daily before my oldest sister passed. I am still very close to my other sister in Texas (I am in MN) and we talk daily. So I would also encourage you not to give up!! Sending positive thoughts and comfort your way!