So sorry to hear about you battling this infection. Yes you need to be taking the Florastor with the antibiotic. Any Saccharomyces Boulardii is good. I was taking three pills per day when I was on antibiotic for c Diff. Make sure you take them two hours apart from the antibiotic otherwise the antibiotic will kill the good bacteria in it. I continued with the S Boulardii post c Diff for few months and I added another probiotic right after I finished the vancomycin. Hope this helps and please ask away! Wishing you a speedy recovery.