John, thank you so much for your reply! I cannot believe that I never thought of the cortisol connection. Of course stress would cause cortisol which would affect blood glucose that is connected to diabetes and the liver. That in itself gives me hope that her numbers now are not necessarily permanent. Her whole married life has been stressful due to the fact that her husband was a recovering alcoholic when they got married and I am sorry to say has gone downhill over the 20+ years they have been married. Losing the house was the last straw and thank heavens that was it. People do not understand why some people stay in bad marriages. Your friends say “Why doesn’t she just leave him?” It’s not that easy and it is tough to be judged. The good thing is that the separation has occurred and that has been when these high readings have spiked. I think she has hit bottom and things will now start to improve. Your input has given me hope.