← Return to Stool consistency while on vancomycin and its significance

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@heatherb821

I hope this sees everyone on this thread.

I’m looking for advice for my 2 year old daughter who has been battling c diff for over a year. She has had 5 episodes of c diff, one Fecal transplant and now on the 6th episode of GDH positive but negative toxins. Her doctor believes she is showing symptoms to the c diff bacteria not necessarily from the toxins so he wanted to treat with vanco again to try killing off the remainder of the c diff. She has had 6 surgeries in her lifetime and only 1 during her c diff battle. We believe she started having c diff infections from all of her hospital stays/surgeries. She also has a colostomy. My questions are, does anyone on here have a colostomy AND c diff issues? If so, what are the stool patterns like? And for everyone who reads this, what are your success stories? How many reoccurrence episodes did it take for you to fully recover from c diff? We have always been on vancomycin-started off with just a 14 day course then as the episodes went on we started to treat with longer tapers after the initial 14 days of full dose. With our last taper lasting 5months long! Our new GI is looking at trying fidaxomycin once the pharmacy gets it in stock and to stop the vancomycin we’re currently on now. I also should add we’re on florastor daily. My daughter usually has pudding to peanut butter thick stool. Does anyone know if vancomycin can cause thicker stools as a side effect? Or is the thicker stool just from the c diff being killed off? Anyone have any thoughts on this? Thank you in advance!

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Replies to "I hope this sees everyone on this thread. I’m looking for advice for my 2 year..."

Hello @heatherb821 and welcome to Mayo Clinic Connect. I can't imagine what your daughter and your family are going through with all of this. It sounds like it has been quite a long road already for everyone.

I am glad you have joined Connect to reach out to others who may be able to provide you with support throughout all of this. Members such as @mhi @euqcaj @lengel and @jeanniesroom have all shared about their c diff experiences before and may be able to help answer some of your questions.

In the meantime, I want to provide you with some resources that may be of interest.

- C. Difficile Care at Mayo Clinic:
https://connect.mayoclinic.org/blog/gastroenterology-and-gi-surgery/newsfeed-post/c-difficile-care-at-mayo-clinic/
And here is another discussion you may find helpful to read through past comments from members:

- Trying to recover from a c diff infection:
https://connect.mayoclinic.org/discussion/i-am-trying-to-recover-from-a-c-diff-infection-this-started-with/?pg=16#comment-247264
- Vancomycin (Oral Route) Side Effects:
https://www.mayoclinic.org/drugs-supplements/vancomycin-oral-route/side-effects/drg-20068893?p=1
How is your daughter doing throughout all of this?