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Any false positive TB blood test results out there?

Infectious Diseases | Last Active: Jun 21, 2023 | Replies (14)
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@aavhad

I have had blurry vision in left eye and Gold quantiferon test came positive they are no other symptoms. Chest x-ray, CT scan, blood work all normal . Eye infection is recovered almost 70-80% after steroid drops prescribed by Retina specialist . Can Gold quantiferon test be false positive ? How soon can I repeat test?

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Replies to "I have had blurry vision in left eye and Gold quantiferon test came positive they are..."
Amanda Roe | @amandajro | Jul 30, 2021

Hello @aavhad and welcome to Mayo Clinic Connect. I see you are looking for some information on false positive. I did a search to see if I could provide any helpful information you may wish to consider and came across the information below.

It is a bit of a heavy read given the research nature of the article, so I pulled out an excerpt that I thought may be helpful for you.

From article:
In realistic settings of low risk of TB infection, even with high cutoffs and confirmation, the post-test probability of a positive QFT test on serial testing may still only approach 60%, while annual testing with a single QFT using the recommended diagnostic cutoff may cause over 25% of individuals to have a false-positive test over a span of ten years.

Serial testing for latent tuberculosis using QuantiFERON-TB Gold In-Tube: A Markov model:
https://www.nature.com/articles/srep30781

Does this resonate with you?

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