Thank you all for your comments. My thoughts were never to avoid Eliquis. I do know it is vital. My concern is whether or not to switch from metoprolol to something else that might have some serious side effects--but might better prevent frequent afib attacks . Unfortunately, the literature is pretty scary about possible side-effects. My doctor has repeatedly assured me afib episodes (I get them about every 2 weeks) have no correlation to enlarged heart or wearing the heart out. Any comments or information? When not in afib, I feel perfectly fine. I do not want the stress of worrying about side-effects on stronger medications. .