allergic reaction to bone cement

Posted by denver @denver, Apr 1, 2019

After 1 1/2 years of pain, swelling getting worse, I was tested for allergies. I will have to have another TKR custom without the bone cement. I am devastated at no one checking for allergies as I have numerous strange food allergies. I am told I may have to wait up to 10 mos for the revision as the FDA only approves a small number of these revisions per surgeons annually. This is because it's not a money maker for the hospitals, so it's limited. Another disappointment as now the hardware is coming loose from the bones and is unstable/more painful. Please pass on my bad experience so others don't suffer. Surgeons should be asking about allergies in this era of more and more people allergic to foods/environmental substances.

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@jenniferhunter

I also had to change my diet to reduce inflammation and I had gluten issues before that was a popular topic among doctors. I went gluten free and worked out all my food issues by doing an elimination diet. It made a huge difference. My husband has eczema that drives him crazy and his fingers crack. It sounds like you are on a good track with your health. I have learned to question everything when there are no obvious answers. Thanks

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Glad diet helped you too. There are so may types of eczema and it sounds like you husband has what my son does, Dysidrotic Eczema, DE which targets the hands and feet causes scaly, plaque like areaw which crack, bleed and peel. Unfortunately it is chronic and only treatments, like steroids which as we all know by know cause side effects like skin thinning and other issues with long term use are prescribed and of course good moisturizing and barrier ointments like Vaseline or Aquaphor (unless allergic to lanolin). My son has had digestive allergies since he was a baby, plus environmental allergies also. I would like my son to attempt an anti inflammation diet like I did with great success, perhaps it could help with DE, yet he is not willing to try that. Also I have not read where diet helps with this form. At least he is one of the lucky ones that doesn't itch from DE, but it does hurt when it cracks. The best site to identify all types of eczema, even rare ones, is dermnetnz.org. I have one common form of eczema, Allergic Contact Dermatitis, ACD, but my other two types are less common, one considered rare and it isn't even listed on US sites when you do an eczema search. The New Zealand site has the best collection of photos, your husband could search under DE and find others with his same symptoms. DE is considered a common form.

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I find this discussion very interesting. I had a partial knee replacement about eight years ago that didn't help reduce my knee pain, so I had a total replacement in October, 2016. About three days later, my liver failed and then I went into multi-organ failure. Long story short, I was life-flighted to SLC for a transplant with only hours left to live. The transplant team couldn't find a reason for the liver failure but said it had to have been a drug interaction from the TKR. I've had many other surgeries with no issues. I've wondered if it could have been caused by the bone cement or the metal of the implant.

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@diana61

I find this discussion very interesting. I had a partial knee replacement about eight years ago that didn't help reduce my knee pain, so I had a total replacement in October, 2016. About three days later, my liver failed and then I went into multi-organ failure. Long story short, I was life-flighted to SLC for a transplant with only hours left to live. The transplant team couldn't find a reason for the liver failure but said it had to have been a drug interaction from the TKR. I've had many other surgeries with no issues. I've wondered if it could have been caused by the bone cement or the metal of the implant.

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I just turned to this comment, and I hope you are feeling better.

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Thanks, Cindi. My knee is horrible. The pain is actually worse than before the TKR. Thankfully, my new liver is doing well.

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@jnoronha

Hello: I wanted to express my disappointment too. My left TKR was done on October 30, 2019. It has been a year and I still get pain in the knee joint. Also I get pain at the back of the same knee and pain in the hip muscle same side. My surgeon tells me every time that I am one of the kind that is taking longer to heal. He says there is nothing wrong. I went for second opinion to another surgeon and he is telling me the same thing. I am just tired of these doctors who cannot tell you why I am getting pain at the back of the knee.

So, what kind of allergy do you have as you said you tested positive when you did allergy testing. Was curious to know.

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Hello, I tested positive for neomycin and
Methyl methacrylate.This is the glue that holds it together. Neomycin is antibiotic. With my surgery they used gentamicin, which is in same family.
Next month it will be 3 years and I am worse off than before! Not sure what I’m going to do.good luck.

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@irish283

Martydav@martydav.
Thank you for your info and happy to hear you had a good experience. Unfortunately I’m located in the northeast, NY. area. I have heard about the press fit through this site.
I am currently re recuperating from rotator cuff surgery two weeks post op. I am leary about doing cementless revision, because if it doesn’t take, I am literally without a leg to stand on!

Good luck with your recuperation!

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I have the same allergy and
I need two TKRs. I have been told by 3 surgeons that they do not recommend cementless replacements. They all said if it doesn’t work, there is no going back…I would be in a wheelchair.

All I can do is try my best to take care of them and have alternative treatments done like nerve ablation.

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@irish283

Hello, I’m new to this site and read about Denver at Denver re their TKR. I too have had a bad experience after my surgery done August 2019. After 2 1/2 mos. of therapy and riding the bike for 15 mins. I suddenly couldn’t make a full revolution. The pain in my knee has always been in pretty much the same area. I have gone to multiple surgeons for “second opinion”. The last dr. I saw suggested I go for allergy testing....I. Came back positive for MMA, methyl methacrylate and neomycin sulfate. I am devastated !! My surgeon literally blew me off when I saw him at 7 mos. post operative I was complaining of same pain. There are so many legal suits pertaining to this cement! Why didn’t they make me go for allergy testing, since this seems to be a problem that has been on going for quite some time! That’s all it would have taken is a simple allergy test. I’m in more pain now than prior to my surgery. Is there anything ELSE that would or could be used in MMA substitution? I can’t believe this is still in use! Why? I don’t know what to do......

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Did you get a blood test for MMA?
I need to be tested and I don't want a patch test since I am missing lymph nodes on one arm and it always blows up when I do patch tests. Thanks in advance.

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@msddsq

Did you get a blood test for MMA?
I need to be tested and I don't want a patch test since I am missing lymph nodes on one arm and it always blows up when I do patch tests. Thanks in advance.

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I’ve only had patch tests.

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Before going through with my knee replacement I told the doctor I wanted testing for all the elements in the implant. That is because I am a very allergic person having Allergic Contact Dermatitis, ACD, which previous testing with the 5 Day Extended Patch test identified almost a dozen elements, natural and synthetic.
He said the best test would be a blood test, but even though I was an allergic person and had positive results on my patch test for acrylics in glues and adhesives, Medicare didn't cover the expense for testing of the implant elements before it was put into your body.
I paid $600 for the blood test, the best money I ever spent. Surprisingly I wasn't allergic to the bone cement, but acrylics aren't in bone cement. However I tested positive to 5 metals. one being chromium, but I was not allergic to titanium, which is one type of metal implant, but chromium and cobalt are also a common implant. The surgeon explained if I went with titanium it is not 100% pure. It still has traces of other metals in the implant. There is also a titanium coated, Gold Implant it is called, which covers the chromium and cobalt, but then again the titanium contains traces of other metals. The implant ages with wear and tear and metal ions are released into the body over time causing allergic reactions. He explained that I could have a ceramic coated implant, but over time the ceramic coated implant also degrades from wear and tear and metals could be exposed yet I could expect many good years before this happened. Hesitant but scheduled surgery. Then I researched the ceramic coated implant he selected, it had a class action lawsuit against it because the bone cement in this implant was loosening, failing to adhere to the patients remaining bones. Go check out how many ceramic coated implants had winning class action lawsuits against them! I canceled my scheduled surgery. Maybe in a few years a better product will be available. At any rate I'd rather deal with the restrictions of my failing knees than living with the pain from an implant/implants my body is rejecting. If the implant would be removed I imagine I would have to be in a wheel chair.

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