Thank you, I was always very healthy until 2 years ago and then diagnosed with an autoimmune disease that caused stage 3 liver cirrhosis. So, taking anything but herbs and supplements was something I had to get used to quickly. I try to do what I can to keep my new liver healthy, while also doing what I can to be able to have my meds reduced.

I believe Envarsus is the time release version of Tacrolimus? So, I take Tac and Mycophenolate as well. I’m sure you know the most important thing is to take it the same time each day and night and the same way, either with or without food.

I’ve read that for the best metabolism taking it on an empty stomach with at least one glass of water is best. But, only if it doesn’t bother your stomach. So, I think it sounds like you’ve got a practice that works for you and clearly you’re doing well at protecting your new kidney...of course the most important thing!

I think a big concern, that many people don’t realize, is that there are so many drugs, herbs, and supplements that interact with Tacrolimus. Many common things like ginger. I’ve attached a couple articles that I found helpful in outlining how drugs are metabolized and what interacts with Tacrolimus. Some, like ginger, I’ll do occasionally, but others like Echinacea I do not take anymore.

As I have three autoimmune diseases, osteoporosis, and neuropathy, and see different specialists, I also check Drugs.com for potential interactions with any meds they suggest. And, I consult with my transplant team prior to trying anything new.