@abrown2 Have you had a complete genetic scan completed on your son? They are getting into the do-able range for most folks now, thanks to Medicare and advanced technology. Dante Laboratories and Sequencing.com are a couple of good places. I have gone through many of the symptoms and procedures, and now I know almost my entire blood kin as wild type myeloma. Mine has ended up with some pretty serious stuff which every doctor except my birth doctor denied I could have. Get that whole genome done. It may save his life from disability and early death.