Wow, so many responses to my original post. Thank you, each of you! The types of side effects that I'm trying to manage (with the assistance of my medical team, of course): Cataracts and lens replacement surgery in both eyes at the age of 45 (Posterior subcapsular, I think), osteoporosis, multiple bone breaks, arthritis in shoulders and knees (at a young age), shoulder replacement attributed due to long term prednisone use..., multiple skin cancers (a gazillion...), moon face, extra tummy weight, etc. I'm 55 presently, and we are working on a plan to protect my kidney (of course) and the rest of my body for the next 30 years. I am physically active, and of course I count my blessings every day of my life for this amazing gift.