← Return to Transplant: Has anyone tapered off prednisone after decades of use?

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@amandajro

Hello @tarmansbks and welcome to Mayo Clinic Connect. I believe you were asking if your body can produce cortisol on its own after tapering off your Rx. I found some information on that topic below that you might find of interest. Notably, the article does state the importance of a slow taper. "A gradual reduction in prednisone dosage gives your adrenal glands time to resume their normal function."

- Prednisone Withdrawal:
https://www.mayoclinic.org/prednisone-withdrawal/expert-answers/faq-20057923
Have you consulted with your doctor about this desire? Why are you interested in tapering?

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Replies to "Hello @tarmansbks and welcome to Mayo Clinic Connect. I believe you were asking if your body..."

I have to ask myself why indeed do I want to wean off. . I have R/A and don't want to take a biologic or infusion therapy. I guess the Medrol is the least damaging. My rheumatologist said I shouldn't be so apprehensive about taking it. I have postpolio sequelae and falling is a concern which I am managing because breaking a bone at my age is also a concern and I have osteopenia (two hip replacements). This is a good topic of interest to me and am glad for the participation. Thank you.

I had read this article weeks ago. Mayo Clinic website is my "go to " for all things medical. Thank you for pointing it out again.