Flyfisherman, allow me to bring fellow heart transplant recipients @estrada53 @danab @scottj and @azdan99 into this discussion. They may have information about drug interactions to share with you.

You may also be interested in this related discussion:
- How much covid protection are transplant recipients really getting https://connect.mayoclinic.org/discussion/how-much-covid-protection-are-transplant-recipients-really-getting/

@dflyfisherman Holi D and welcome.to Connect. I'm in the same category as you when it comes to the Vaccine and while im a believer in Vaccines in general I think when it comes.to the Covid Vaccine we are learning all thee time. I have posed the question you mention to my Infectious Disease Doctor and yes it seems they are finding it's best to receive the vaccine prior to transplant but for most of us who had them.in the past it's true that it seems they are less effective.
Now the good news is along with vaccines there is ongoing studies in treatment.options also and my doctor mentioned a study looking very promising called Monoclonal Antibodies which if we catch it and treat it early.has shown great success. So as we all know when we received.our transplant that we would have to be more diligent in the protection area that's my general advice along with my doctors. Mask, wash hands and distance are still our best defense. That's what I've been told lately and not to say the vaccine has no protection just reduced. I've heard figures of 30 to 50 % effective. But im at. least very confident that our Mayo Doctors are working diligently to find options.
I hope that helps
Have an awesome Day
Dana