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Constant tinnitus: Are there any solutions?

Ear, Nose & Throat (ENT) | Last Active: Oct 30, 2023 | Replies (183)

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@lacy2

@willows Thanks. Many years ago first visit to Neurologist for head rushes he gave me Amitriptyline... next morning I was very distressed plus the cotton mouth so didnt keep taking; then a few years ago I had my DNA done and right at top of list it says under "Major gene-drug interaction" 5 drugs under Psychiatry and first one is Amitriptyline... so my body was not wrong those years ago... but I dont see Pregabalin/lyrica in the report - wish it was on a usb stick so I could search on internet. Metoprolol is on the list as "moderate gene-drug interaction under Cardiovascular?
I really dont understand all of this report except it says I am TPMT genotype with DPYD but no one followed up on the Report and it sits here gathering dust!
Tinnitus is almost 24/7 now with pain and a bit of tmj no doubt... and in itself used to be able to cope with but with other medical issues and old age it's changed my life as I knew it. 🙁

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Replies to "@willows Thanks. Many years ago first visit to Neurologist for head rushes he gave me Amitriptyline......"

Hi Lacy, I am sorry for everyone who has tinnitus. I have had it 24/7 for 30 years. I can’t comment on the scientific matters and am not sure what you meant about gene drug interaction or TPMP or DPYD but will search on the internet. My comments were in the nature of « this helps a bit » not what causes this to help me. It’s no magic bullet however. I take the Medication called metoprolol because it helps eliminate occasional mild irregular heartbeats caused, I think, as a side effect of the amitriptyline.

Willows