Hi, @scrappie08 - welcome to Mayo Clinic Connect. I can't imagine having your spouse and best friend change into a completely different personality with temper, anger, jealousy and acting inappropriately. Sounds like while you are hurting and having challenges with living with a spouse who is exhibiting these behaviors so far from what she used to be, you are also trying hard to stand in her shoes and look at her experience with bipolar, PTSD and now a personality disorder from her perspective.

I'd like to introduce you to @amberpep, who has talked about bipolar, as well as @parus @gingerw @beckysn @mblbirch. Hoping they can identify with some of what you and your wife are experiencing and also provide some support to you and any input they have to offer.

Why are you feeling it's too late to try and get things under control, as the doctor mentioned? Are her current medications helping at all with the symptoms she has?