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@aknitag

Hi.. my husband has Stiff Person syndrome.. diagnosed about 2 yrs ago.. he had been having problems swallowing and charlie-horse type spasms mostly in is neck and over his rib cage... he has the raised GAD, was confirmed... also.. in checking out the spasms/chocking on food, they did MRI that accidentally discovered a brain tumor just behind and between his eyes (size of golf ball), meningioma non cancerous.. had that removed successfully in April of 2018.. He is on valium and gabapentin.. Some days are good and some days are bad.. I was wondering if stiff-person syndrome is related to some other brain disorders.. I know that ALS, alzheimers, parkinsons are nerve degenerative disorders and treatment with L-serine is now under clinical tests that look very promising... Does anyone know if this could help stiff person?

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Replies to "Hi.. my husband has Stiff Person syndrome.. diagnosed about 2 yrs ago.. he had been having..."

Hello @aknitag, welcome to Mayo Clinic Connect. Thank you for being a strong advocate for your husband's health and searching for answers. It's good to hear that he has good days along with the bad ones. I'm hoping someone more knowledgeable about stiff person syndrome can provide some information on your question is it related to other brain disorders. It does seem like it's likely but I have no medical background or training. Here are a few links that may provide some answers for you.

Stiff-Person Syndrome Information Page -- https://www.ninds.nih.gov/Disorders/All-Disorders/Stiff-Person-Syndrome-Information-Page

9 Studies found for: Stiff-Person Syndrome -- https://clinicaltrials.gov/ct2/results?term=Stiff-Person+Syndrome

Have your husbands doctors suggested any other treatments or therapy?