It took about 2-3 months to find the right dose of cannabis. Everyone responds differently, so if you decide to go this route, work with the dispensary, keep a journal of what you are using, the route (vape, gummies, etc), how often and the dose. You have to experiment and find what works for you. If I need immediate relief (10-15 mins) I vape, to get me through the night I use gummies or tincture. The gummies and tincture take about 45 mins to work, but the impact last about 6-7 hours. Again this is my situation. The 1:1 ratio of THC and CBD is the only combination that relieves and prevents my spasms.