Hello @grand4. I would like to invite @maisyann, @mepowers, @ladygolfder18, and @dougmann who also have experience taking rituxan (rituximab). @dougmann also has some experience with spleen pain.

@grand4, if you don't mind me sharing, was removing your spleen discussed with you as a potential treatment?

I was diagnosed with splenic marginal zone small b cell lymphoma in April of 2017. The Doctors at Mayo Rochester removed my enlarged spleen July 2017. In September 2017 I had another bone marrow biopsy and flow cytometry and the lyphoma was still in the bone marrow. In October I started 4 weeks of Rituxan. Had no side effects to the Rituxan. After the Rituxan the lymphoma is now gone but I still have night sweats and fatigue . I am now on wait and watch until the end of January next year.

I have just been diagnosed with a Splenic cyst and an enlarged spleen and liver. Awaiting results of CT scan next week with interest to see if my Indolent Follicular Lymphoma is back. I was originally diagnosed in August 2000. Relapsed with an extra nodal tumour on my scalp in March 2012.

I was diagnosed with SMZL in December of 2018. I've had several iron infusions but nothing else. I am starting to have some pain where my spleen is but my biggest problem is hurting all over my body and chronic fatigue. The last week or so I have been running a low grade fever on and off. Does anyone else have those types of symptoms? Since this is so new to me, I'm not sure if it's something else or related to the SMZL. My next visit with my Oncologist is next month and I will talk with him also. Thank you

@caroldk I see you are new to connect welcome.
Although I do not have the same lymphoma or symptoms as you have. Fatigue, and pain I believe is are symptoms, some patients do experience from time to time.
I do recommend you contact your Dr's office. Were you experiencing these symptoms prior to Dec? Or have they started since getting iron infusions?
You could also have been exposed to the flu? Cause we have low resistance to viruses.
Please contact your DR, and let us know what he says if you can?

I wish you the best.
Jackie

@caroldk are you able to get a second opinion from Mayo Clinic. They have a HUGE building and wing they just built in Jacksonville. Fl. They have all kinds of studies going on specifically geared towards Lymphoma. Can you reach out to them for a consultation? They also have facilities in Phoenix and Rochester, Mn. Maybe one of the Dr's there can help you? Or they have a study you can get in that maybe of benefit to you?

Does soaking in a warm bath help your symptoms at all? Or maybe applying some Ben Gay to the sore spots?

I wish you the best.
Please keep us posted, but do call your DR and see if he can give you some answers and help to alleviate your symptoms.

Praying you get relief..
And I hope you have a Nice Valentine Day..
Jackie