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Sinemet (Carbidopa-Levodopa): Does it help for burning legs at night?

Parkinson's Disease | Last Active: Mar 5, 2021 | Replies (10)
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@hopeful33250

Hello @robtlhughes

I've used carbidopa/levodopa for many years for a Parkinson's disorder. I've not heard of it used for problems with burning legs caused by neuropathy. If you are comfortable sharing more could you share what tests you have had to diagnose the problem with burning legs at night? I'm thinking of vascular testing of the legs, etc. Is your prescribing doctor a neurologist? Have you tried other meds for this problem or is this the first med you have used?

Carbidopa/levodopa, used by PD patients has the unfortunate side effect of dyskinesia when used over a long period of time. As you may know, dyskinesia is a movement disorder that makes it hard to be still, there is a jerkiness all over your body. Here is an article from WebMD about dyskinesia that you might find interesting.

https://www.webmd.com/parkinsons-disease/prevent-dyskinesia

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Replies to "Hello @robtlhughes I've used carbidopa/levodopa for many years for a Parkinson's disorder. I've not heard of..."
robtlhughes | @robtlhughes | Mar 5, 2021

Thanks for your interest and for getting back with useful information. The medication was not prescribed by a neurologist. I've been seen by neurologist at two well-regarded teaching hospitals. The doctor at one said the chance of anything helping was "vanishingly small." The other wants me to hurry back to Pittsburgh for more tests, probably to see how fast I'm going down. But a family doctor thought the med might be worth a limited try. After three nights of trying, reading the package insert, consulting with Dr. Google and now reading your post, the test has now concluded. Thanks again.

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