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Sinemet (Carbidopa-Levodopa): Does it help for burning legs at night?

Parkinson's Disease | Last Active: Mar 5, 2021 | Replies (10)
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@robtlhughes

I've been taking 100 mg at bedtime for a couple days. I'll take it for a week to see if it helps. The doctor, I think, suspects restless leg syndrome might be a work. I'm skeptical, but think it's worth a try, but for no more than a week. The medication is usually prescribed for Parkinson's Disease and restless leg. I've not heard of its use with peripheral neuropathy which is why I posted my question.

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Teresa, Volunteer Mentor | @hopeful33250 | Mar 5, 2021

Hello @robtlhughes

I've used carbidopa/levodopa for many years for a Parkinson's disorder. I've not heard of it used for problems with burning legs caused by neuropathy. If you are comfortable sharing more could you share what tests you have had to diagnose the problem with burning legs at night? I'm thinking of vascular testing of the legs, etc. Is your prescribing doctor a neurologist? Have you tried other meds for this problem or is this the first med you have used?

Carbidopa/levodopa, used by PD patients has the unfortunate side effect of dyskinesia when used over a long period of time. As you may know, dyskinesia is a movement disorder that makes it hard to be still, there is a jerkiness all over your body. Here is an article from WebMD about dyskinesia that you might find interesting.

https://www.webmd.com/parkinsons-disease/prevent-dyskinesia
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