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Rising PSA years after radical prostatectomy

Prostate Cancer | Last Active: Mar 5 7:14am | Replies (206)

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@colleenyoung

@olanordman, you may also wish to read these related discussions:
- Post prostatectomy: What do rising PSA levels mean? https://connect.mayoclinic.org/discussion/post-prostatectomy/
- High PSA three years post op https://connect.mayoclinic.org/discussion/high-psa-three-years-post-op/
- PSA numbers: Questions about new treatments https://connect.mayoclinic.org/discussion/psa-numbers/
- Follow up after proton beam treatment: GREAT PSA NUMBER https://connect.mayoclinic.org/discussion/great-psa-number/

You ask a good question. What can rising PSA levels means years after having had a prostatectomy?
There are several reasons why one's PSA level may rise after being stable for a time. This article explains it well:
– PSA levels after prostatectomy https://www.medicalnewstoday.com/articles/323899.php

Here's an excerpt from the article:
"Seeing a rise in PSA level does not always mean that prostate cancer is returning or spreading. The test is very sensitive and can pick up small changes in PSA levels. Doctors will usually want to know how quickly levels of PSA in the blood are rising. To find this out, a person will need to have regular PSA tests. If levels of PSA remain stable or rise very slowly, treatment may not be necessary.

In some cases, high PSA levels in the blood are not due to cancer cells. Some factors that can affect PSA levels include:
– older age
– ethnicity
– medication
A doctor will take these factors and the person's medical history into account when looking at test results. This can help them decide if PSA levels are high enough to cause concern."

The PSA test alone is not enough to determine cause or next steps. Your oncology team will consult with you and likely order other tests. Did you have other treatments after surgery?

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Replies to "@olanordman, you may also wish to read these related discussions: - Post prostatectomy: What do rising..."

Hello. Thanks for your input. I just came across this information on a sheet after my surgery to remove the postrate. I had to go to an online portal to get this information

It states STAGE pT2pN1a. What does this really mean?

8 lympth node taken from left. only 1 lympth node showed 1mm long micrometasis with Gleason grade 3

6 lympth nodes taken from right no any metasiss

This is written in Norwegian but I tried to interprete it.

Yet to get an appointment as I was referred to a radiologist to assess if I need radiation. My PSA is 0.18. I am booking an appoint for another test

12.12.2019 0.12
17.04.2020 0.12
21.08.2020 0.11
22.10.2020 0.17
22.12.2020 0.15
22.02.2021 0.18

Regards

Thanks Colleen. No treatment after rp. Consulting w urologist on ,28. Doing another psa next week. I appreciate any info u can provide

Hi. I had radical surgery Oct 2019. Lots of high numbers. Gene testing predicted 5.9%chance of reoccurrence in 10 years. 16 months later cancer came back in lower abdomen. 35 Radiation treatments, radiation cystitis, Peeing blood and huge clots. 40 hyperbaric oxygen chamber therapy sessions to stop bleeding. Lots of other problems. Total incontinence. Had artificial sphincter installed Aug 2021. Failed at 3 weeks. Dec surgery to switch sides of the pump. Fail. Cuff had eroded into my urethra, causing infections. Feb 22 had it all removed. One failure after another. PSA after 2 years is still undetectable. The only good thing out of all this. Good luck,