Does H. Pylori lead to stomach cancer?

Posted by hogan_g1937 @hogan_g1937, Jun 25, 2018

Good afternoon to all, My husband was recently treated for HCC with chemotherapy and radiation. He was recently treated for H Pylori bacteria. in a month he will need to take a breath test to see if the bacteria is gone. I know that this type of bacteria can cause stomach cancer. Has anyone diagnosed with this bacteria led to stomach cancer? Any information on this topic will be appreciated. I fear that he has stomach cancer due to some of the symptoms listed. Hopefully I am over thinking this.

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Profile picture for kidprodigy @kidprodigy

BACKGROUND:

I was diagnosed with a Helicobacter Pylori (H. Pylori) infection in my stomach back on July 1, 2020 after nearly a year of living undiagnosed and in constant pain.

Since receiving a diagnosis, I've taken multiple rounds of combination antibiotics therapy for my infection. They include:

2 x 14-day rounds of clarithromycin triple therapy (generic PrevPac)
2 x 10-day rounds of Pylera (bismuth quadruple therapy)
1 x 14-day round of bismuth quadruple therapy (generic Pylera)

Though my health has improved about 60%-70% since completing almost 9 weeks of treatment, I've decided to continue with therapy until the H. Pylori infection is fully eradicated.

My GI specialist just prescribed a 14-day round of Talicia therapy which I will begin taking tomorrow. Talicia was FDA-approved in 2019 and just launched in the US market back in March 2020 so it's a relatively new drug.

QUESTION(S):

1. Has anyone suffered from an H. Pylori infection? If so, what combination antibiotics therapy did you use to fully eradicate it?
2. Has anyone taken Talicia therapy? If so, was it effective and what were the side-effects?

Thank you for reading this post and providing your helpful feedback!

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I was treated with amoxicillin-clarithromycin-lansoprazole for 14 days and that cured my H Pylori. I was tested for it during my EGD and it came back negative.

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Profile picture for kidprodigy @kidprodigy

Have you ever had an H. Pylori urea breath test or stool antigen test to confirm eradication post-treatment? If so, what were your test results?

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No this is my first round of talicia I will be retested in 30days with breath test

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h pylori infection

Has anyone found a natural treatment and cure for the h pylori infection? My hesitation in taking antibiotics is that they kill off good bacteria in the gut, regardless of taking probiotics.

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Profile picture for collage @collage

h pylori infection

Has anyone found a natural treatment and cure for the h pylori infection? My hesitation in taking antibiotics is that they kill off good bacteria in the gut, regardless of taking probiotics.

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Hey, my dad had a major ulcer problem. He did take antibiotics (amoxicillin and bismuth something. Its been a while so I apologize I forgot the name). In terms of diet, I made him drink a lot of fluids and he had some fermented rice and yogurt Anything with a lot of probiotics is very good. In fact, a lot of stores sell probiotic dummies which you can try using. Broccoli is very good source too for h pylori coupled with white meat. I also faintly remember learning that lactoferrin in milk helps with h pylori infection so you could try that. The trick is clean foods coupled with a lot of fluids and medication. There isn't one magic silver bullet. Hope this helps!

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@arrikanna & @arrikanna Welcome to Mayo Clinic Connect, a place to give and get support

@arrikanna Thank you for telling us your father's experience. May I ask what brings you to Mayo Connect?

@collage H. Pylori can be a serious infection and it's important to gather all of the information needed. I have had H. Pylori. I did my homework and I found out that the likelihood of having stomach cancer greatly increases with the number of times you have had H. Pylori. This was disturbing news to me. I was lucky in that the antibiotics agreed with me and I was able to get rid of it with only 1 course. This is not the case for a lot of people. Just an aside, I'm sensitive to a lot of medications and these 3 antibiotics were fine, everyone is different though.

You'll notice that I added your question to an existing discussion. I did this so you could connect with members that have experience with this topic. Below I have also linked another previous discussion on the topic. You may wish to scroll through these discussions to find information and connection.

- I was treated for h pylori. Stool test now negative https://connect.mayoclinic.org/discussion/hello-i-was-treated-for-h-pylori-by/

May I ask if you have an alternative medicine professional that you work with currently?

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Profile picture for Erika @erikas

@arrikanna & @arrikanna Welcome to Mayo Clinic Connect, a place to give and get support

@arrikanna Thank you for telling us your father's experience. May I ask what brings you to Mayo Connect?

@collage H. Pylori can be a serious infection and it's important to gather all of the information needed. I have had H. Pylori. I did my homework and I found out that the likelihood of having stomach cancer greatly increases with the number of times you have had H. Pylori. This was disturbing news to me. I was lucky in that the antibiotics agreed with me and I was able to get rid of it with only 1 course. This is not the case for a lot of people. Just an aside, I'm sensitive to a lot of medications and these 3 antibiotics were fine, everyone is different though.

You'll notice that I added your question to an existing discussion. I did this so you could connect with members that have experience with this topic. Below I have also linked another previous discussion on the topic. You may wish to scroll through these discussions to find information and connection.

- I was treated for h pylori. Stool test now negative https://connect.mayoclinic.org/discussion/hello-i-was-treated-for-h-pylori-by/

May I ask if you have an alternative medicine professional that you work with currently?

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I have been doing quite a bit of research and have been combining yoga with a variety of herbal treatments, dietary supplements; probiotics, fermented foods, and a change in diet. My symptoms are occasional and generally mild, depending on what I eat. I have eliminated caffeine, most dairy products, sugar or sugar substitutes, and have reduced consumption of red meat. I am scheduled for an endoscopy and will rely on the recommendations following that procedure. (H-pylori infection was confirmed by a blood test a few months ago, but I believe I have had this for about a year.)

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Profile picture for collage @collage

I have been doing quite a bit of research and have been combining yoga with a variety of herbal treatments, dietary supplements; probiotics, fermented foods, and a change in diet. My symptoms are occasional and generally mild, depending on what I eat. I have eliminated caffeine, most dairy products, sugar or sugar substitutes, and have reduced consumption of red meat. I am scheduled for an endoscopy and will rely on the recommendations following that procedure. (H-pylori infection was confirmed by a blood test a few months ago, but I believe I have had this for about a year.)

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Oh I see. Im sorry that I didn't answer your question earlier about taking antibiotics and whether or not if it will kill off good bacteria along with harmful. The short answer is it depends on the person, it will kill some of good bacteria, but the benefits far outweigh the risks. As you may know, the gut is home to a variety of species of bacteria. In a healthy person, a majority of the species are good while some are bad. However, its not like all good bacteria are one species and that the antibiotic will kill all of them. Think of it like its own ecosystem with different species. There are species of bacteria that are unique from each other that are both good. So antibiotics can affect some species, but not others. However, each person has a unique composition of species. We all don't have the same amount of bacterial species as the other, so medication can affect each person differently.

The best thing to do is to take the antibiotics given by your doctor while continuing your healthy regiment. Monitor your intake carefully and if you feel a negative change, consult with your doctor immediately and they can prescribe different antibiotics to help. Unfortunately, many aspects of medicine is trial and error. With your regimen and continued use of antibiotics, you should see good results! Hope this clears up some confusion.

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Profile picture for Erika @erikas

@arrikanna & @arrikanna Welcome to Mayo Clinic Connect, a place to give and get support

@arrikanna Thank you for telling us your father's experience. May I ask what brings you to Mayo Connect?

@collage H. Pylori can be a serious infection and it's important to gather all of the information needed. I have had H. Pylori. I did my homework and I found out that the likelihood of having stomach cancer greatly increases with the number of times you have had H. Pylori. This was disturbing news to me. I was lucky in that the antibiotics agreed with me and I was able to get rid of it with only 1 course. This is not the case for a lot of people. Just an aside, I'm sensitive to a lot of medications and these 3 antibiotics were fine, everyone is different though.

You'll notice that I added your question to an existing discussion. I did this so you could connect with members that have experience with this topic. Below I have also linked another previous discussion on the topic. You may wish to scroll through these discussions to find information and connection.

- I was treated for h pylori. Stool test now negative https://connect.mayoclinic.org/discussion/hello-i-was-treated-for-h-pylori-by/

May I ask if you have an alternative medicine professional that you work with currently?

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Hi ma'am. I heard this from a mutual friend. I have a major interest in infectious diseases and have ample experience handling bacterial species in both a lab setting and dealing with patients clinically. Apart from that, a lot of my family members have passed away from bacterial infections due to them not understanding how it works and not having good hospital care. Its something I am very personally attached to so I try to help other people understand and help them not feel overwhelmed and confused through this process.

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Dear Mayo Clinic Connect Members,

I regret to inform you that I do not have nor have I ever had an H. Pylori infection according to this negative H. Pylori IgG/IgA/IgM antibody blood test. I told everyone around me that I finally had a diagnosis until now. 😢

I tested negative for H. Pylori on biopsy by upper endoscopy procedure, 15-20 urea breath tests and 10-15 stool antigen tests over the past 6-9 months. For these reasons I’m giving up on an H. Pylori diagnosis and all of my doctors have dismissed it now, too.

However, my symptoms fit an H. Pylori infection, chronic gastritis/duodenitis were discovered on upper endoscopy and I respond well to H. Pylori treatment. This leads me to believe I have a different infection in my upper GI tract and it’s either bacterial or parasitic in nature. 🦠

I’m working with a new specialist now and I’d like your thoughts on an alternative diagnosis. What bacterial or parasitic infections in the upper GI tract are chronic and produce symptoms that mimic an H. Pylori infection??

Also, I'm struggling to locate an infectious disease physician who specializes in diagnosing and treating parasitic infections in the North Texas region. Can you recommend someone for me? If so, please forward me his/her contact information so I can schedule a new patient appointment right away.

Thanks for your feedback!! 🙏

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Profile picture for kidprodigy @kidprodigy

Dear Mayo Clinic Connect Members,

I regret to inform you that I do not have nor have I ever had an H. Pylori infection according to this negative H. Pylori IgG/IgA/IgM antibody blood test. I told everyone around me that I finally had a diagnosis until now. 😢

I tested negative for H. Pylori on biopsy by upper endoscopy procedure, 15-20 urea breath tests and 10-15 stool antigen tests over the past 6-9 months. For these reasons I’m giving up on an H. Pylori diagnosis and all of my doctors have dismissed it now, too.

However, my symptoms fit an H. Pylori infection, chronic gastritis/duodenitis were discovered on upper endoscopy and I respond well to H. Pylori treatment. This leads me to believe I have a different infection in my upper GI tract and it’s either bacterial or parasitic in nature. 🦠

I’m working with a new specialist now and I’d like your thoughts on an alternative diagnosis. What bacterial or parasitic infections in the upper GI tract are chronic and produce symptoms that mimic an H. Pylori infection??

Also, I'm struggling to locate an infectious disease physician who specializes in diagnosing and treating parasitic infections in the North Texas region. Can you recommend someone for me? If so, please forward me his/her contact information so I can schedule a new patient appointment right away.

Thanks for your feedback!! 🙏

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I had H Pylori infection along with a bleeding ulcer and chronic gastritis. I got rid of the H Pylori and ulcer but can't shake the chronic gastritis. Let me know if you ever get rid of the chronic gastrtis.

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