@almula

It’s generally recommended to not take any aspirin, acetaminophen, or ibuprofen products right before the covid vaccine because it could effect the response from the vaccine by muting the body’s natural inflammatory response. Maybe that’s what the doctor had in mind? Being a transplant patient, we’re already on immunosuppressants so adding the aspirin to the mix probably won’t make much difference and it’s important for you to stay on your prescribed meds.

Here’s an excerpt from the CDC guidelines about avoiding these meds beforehand:

“Considerations for taking medication before getting vaccinated
For most people, it is not recommended to avoid, discontinue, or delay medications for underlying medical conditions around the time of COVID-19 vaccination. However, your healthcare provider should talk to you about what is currently known and not known about the effectiveness of getting a COVID-19 vaccine when taking medications that suppress the immune system.

It is not recommended you take over-the-counter medicine, such as ibuprofen, aspirin, or acetaminophen, before vaccination for the purpose of trying to prevent vaccine-related side effects. It is not known how these medications may affect how well the vaccine works. However, if you take these medications regularly for other reasons, you should keep taking them before you get vaccinated. It is also not recommended to take antihistamines before getting a COVID-19 vaccine to try to prevent allergic reactions.”
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/expect.html