@almula,
I am also a transplant recipient (liver/kidney 2009) and I take a daily baby aspirin per advice of my transplant doctors and my primary care physician. I have had 2 doses of the Pfizer Covid19 vaccine.

I cannot find any reports that the baby aspirin should be discontinued, and I have not been advised to make any medication changes prior to my vaccinations.. However, I do respect that some people might be directed to do otherwise based on their own unique conditions. Of the articles that I have read in the past, it seems that many people are taking baby aspirin without consulting their doctor first. I wonder if this is what the Saudi doctor has in mind?
What do I think? I think that Mayo would have advised me about medications when I asked my nurse coordinator about getting the vaccine when it became available locally for me.

@almula

It’s generally recommended to not take any aspirin, acetaminophen, or ibuprofen products right before the covid vaccine because it could effect the response from the vaccine by muting the body’s natural inflammatory response. Maybe that’s what the doctor had in mind? Being a transplant patient, we’re already on immunosuppressants so adding the aspirin to the mix probably won’t make much difference and it’s important for you to stay on your prescribed meds.

Here’s an excerpt from the CDC guidelines about avoiding these meds beforehand:

“Considerations for taking medication before getting vaccinated
For most people, it is not recommended to avoid, discontinue, or delay medications for underlying medical conditions around the time of COVID-19 vaccination. However, your healthcare provider should talk to you about what is currently known and not known about the effectiveness of getting a COVID-19 vaccine when taking medications that suppress the immune system.

It is not recommended you take over-the-counter medicine, such as ibuprofen, aspirin, or acetaminophen, before vaccination for the purpose of trying to prevent vaccine-related side effects. It is not known how these medications may affect how well the vaccine works. However, if you take these medications regularly for other reasons, you should keep taking them before you get vaccinated. It is also not recommended to take antihistamines before getting a COVID-19 vaccine to try to prevent allergic reactions.”
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/expect.html

@almula Before my doses of vaccine, I took myself off over-the-counter pain relief medications, after reading and seeing reports that it was advisable to do so. All other medications [both OTC and Rx] were kept in place. This worked fine for me!
Ginger