Kathy, like others on this board you've discovered that 7% rocks. My experience is similar to Sue's in that since beginning 7% the 2 to 3 exacerbations each year have gone bye bye. Currently about 15 months sans flare-up. I use a percussion vest along with the nebulizer. Re: the intrusion into one's daily life and the time it takes. It may seem odd, but I've come to "enjoy" the Thumper time, using it to check the news feed on the iphone, work on a crossword, or occasionally crank out a piece of whimsy like "Ridin' ole Thumper again or a visit from St. Thumper on Xmas eve. Perhaps I should acknowledge that all this is probably easier for me than for many others since I'm fully retired and haven't any children in the house so my daily life has fewer claims on available time. Interacting with people on this board is a gratifying experience as well. Which reminds me; Sue I definitely vote for "Wreeping." What a word! LOL, Don