Going Beyond Standard Immunotherapy

Posted by Tom Anderson @ta52, Dec 9, 2020

In my doctor's consult yesterday I was told that because I was tolerating the infusions so well with little or no side effects they want to go beyond the standard four infusions and continue with a Keytruda/Alimta "cocktail". Is this normal? Has anyone else been through this and what were the results?

Interested in more discussions like this? Go to the Lung Cancer Support Group.

Profile picture for dutchw @dutchw

Thanks for your quick response. For the past year we have been draining a pint of fluid, 1/2 quart, off one lung every 3rd day. Have a catheter in the right lung. My wife is a retired RN so we drain it at home. I’m not going to let them do a procedure to close the space the fluid is accumulating until they tell me what is causing the fluid. That’s why I was inquiring here. It doesn’t hurt, just inconvenient. I don’t want to stick my nose into anyone’s business but my oncologist informed me more than once, while taking Keytruda/immunotherapy DO NOT take any vaccines. Has your Dr approved?? Stay safe.

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I'm Hoping there will be replies to those oncologist patients taking vaccines. As I understand it's live vaccines that may not be approved. We have been told that all oncology patients need to be vaccinated for Covid 19/

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I received my first shot yesterday. Only a little sore were needle went in. Still early. Colleen

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I was on 4 types of chemo and after 7 months went on keytruda and been on that over one year.

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Profile picture for richcolleen @richcolleen

I was on 4 types of chemo and after 7 months went on keytruda and been on that over one year.

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Hi there, When will we play again? I am glad to see your name today. Don’t forget that if you need transportation, let me know. We just got the vaccine....shot #1. Hope you feel well.
Chris

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Profile picture for michaelw9dy @michaelw9dy

I'm Hoping there will be replies to those oncologist patients taking vaccines. As I understand it's live vaccines that may not be approved. We have been told that all oncology patients need to be vaccinated for Covid 19/

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Hmmmm , I just checked, it is not a live virus in the shot.

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Profile picture for Merry, Alumni Mentor @merpreb

@dutchw- Good morning and Welcome to Mayo Clinic Connect. Thank you for sharing your story. I am a mentor for Mayo Connect's Lung Cancer and Lung Diseases. I have an unusual lung cancer called Multifocal Adenocarcinoma. I have survived two types of lung cancer for 23+ years and have never had immunotherapy, although I have had chemotherapy. I am sorry if I have given the impression that I have taken this wonderful drug.

@miriam57; @richcolleen- I have found that many people who have finished their two years on Keytruda are followed very closely with CT scans. I am at a loss to tell you that there are other drugs right now that will maintain you. Keytruda is "Humanized antibodies" This means that they are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants produced naturally in humans. I certainly hope that the positive outcomes for many people who have taken this drug will see many more and maybe even a possibility for a maintenance program. I just don't know of any at this time.

The developers for Keytruda limited the study to two years. There was a lot of competition between several drug makers for the success of such a drug. You can read more of this here:
https://en.wikipedia.org/wiki/Pembrolizumab
The reason that I am suggesting that you read Wikipedia about your drug is so that you can see why there was a 2-year limit.

I am very glad that this drug's targeted population has expanded into many cancers.
https://www.keytruda.com/

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I just want to take time and thank you for being here Merry !!! Whenever I start feeling down about surviving or reoccurrence of my lung cancer I read your 23+ year survival story. It perks me up, gives me hope as I’m sure it does others on this site. At my age, if I make it 23 more years I’ll be 104 years old lol.. Thank you, your a God sent.

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Profile picture for dutchw @dutchw

I just want to take time and thank you for being here Merry !!! Whenever I start feeling down about surviving or reoccurrence of my lung cancer I read your 23+ year survival story. It perks me up, gives me hope as I’m sure it does others on this site. At my age, if I make it 23 more years I’ll be 104 years old lol.. Thank you, your a God sent.

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@dutchw- Oh, my goodness. Not to blow my own horn but survivorship is what hope is all about. When one of us survives it gives hope to others, a willingness to move ahead. Thank you.

By the way, 104 is a lofty goal, go for it!

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Merry.. Good morning.. I’ve seen the term “ground glass” a number of time. What does that mean, please?

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@dutchw- Good morning! Ground Glass is a descriptive term used in describing the look of certain lung cells. It helps with a diagnosis. It looks like a faint cloud of tiny glass particles.

Have you run into this term in relation to yourself?

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