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Allow me to be the acronym buster (self-proclaimed 🙂
MPN = Myeloproliferative neoplasms, a group of diseases that affect blood-cell formation.
ET = Essential thrombocythemia, an uncommon disorder in which your body produces too many platelets.
PV = polycythemia vera, a blood disorder in which the body makes too many red blood cells.
MF = Myelofibrosis, an uncommon type of bone marrow cancer that disrupts your body's normal production of blood cells.
(ST, I believe this was a typo for ET.)

The JAK2 mutation is acquired and not inherited. People are not born with this mutation, but instead develop it in their bone marrow cells sometime later in life. @pattitoo, I would question your doctor about this and encourage you to get clearer answers.

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Replies to "Allow me to be the acronym buster (self-proclaimed :) MPN = Myeloproliferative neoplasms, a group of..."

Colleen - thank you - those are going to be helpful. No doubt - I am not getting much needed information from the current doctor.
And he say I was born with it.
Recently I had a lot of blood work done - was applying for life insurance, everything was good, Blood work excellent,

A QUESTION: Is it normal to have "what ever I have" and have normal blood work? The testing for blood was most I have had done in years. I would think some areas would be out of range.

My husband was just told by the hematologist he was referred to that he has Jak2 mutation and is awaiting bone marrow biopsy. He is 52 yrs old and I am a nurse who never heard of this. Last month he had been diagnosed with his first bout of diverticulitis, and has yet to follow up with getting a colonoscopy that he was recommended to have. The diverticulitis is the reason they did a blood panel & was referred to hematologist. Reading up on what JAk 2 is, I have become quite anxious and I want answers now. I don’t even know what questions to ask. Any advice would be so helpful. Thank you