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gg17 (@gg17)

Cyclosporine and kidney issues

Blood Cancers & Disorders | Last Active: Nov 8, 2020 | Replies (4)

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@gingerw

@gg17 Good morning! I read through your previous posts with AIHA. Have you had any history of kidney issues before, or signs of compromised kidney function? Not knowing how long you have been on cyclosporin [usually used for organ transplant immunosupressant], was there baseline labwork done before starting it? If it were me, personally, I would check with my doctor, and let them know your concerns. The kidneys are fairly sensitive organs, and pretty critical to good health.

Please let me know what your doctor has to say about the creatinine levels, and your kidney health in general. Sometimes we have to take a medication to treat a condition, that may compromise something else.
Ginger

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Replies to "@gg17 Good morning! I read through your previous posts with AIHA. Have you had any history..."

Prior to the CLL rearing it’s head, my kidney function was good. I had creatinine levels around 1.0, but no kidney damage. I had a lot of muscle mass from exercise and weight lifting. Then after hospitalization I lost muscle mass and creatinine levels were about .8. So my GFR was 90 prior to cyclosporin. I developed AIHA, PRCA (parvo), neutropenia and thrombocytopenia (platelets remain around 100,000). The cyclosporin is for the PRCA. The CLL was knocked down in March with rituxan. I am currently seeing a specialist at Mayo. He monitors my creatinine, but I am still concerned because it has been as high as 1.5 and 1.3. Some things I have read state that cyclosporin can cause vasoconstriction and a temporary rise in creatinine. What do I believe?

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