@waynen @frankstags I had only one Lupron shot ..initially after the diagnosis at Mayo MN. I did the 20 radiation treatments in central Iowa where the Radiation Oncologist (his first doctorate was in Nuclear Physics) had trained with the Mayo Doc.. and the Machine in Iowa was similar.., A newer twist was that they injected a spacer material between the prostate and the bowel.. that Spacer was to go away.. but during the treatments the targeting is so close and accurate that the 1/2" they moved the bowel was supposed to help prevent a lot of diarrhea problems. It seems as if the spacer helped as my older brother had 40 low dose treatments a decade ago and had terrible side effects... After I finished the radiation (now a year ago) the Oncologist said they were not going to do the 2nd Lupron.. but I still have some side effects.. but quarterly check-up PSAs were around 0.5... Ken