I’ve been taking it since May 2020. I won’t know until my next checkup about how well it’s working. I do know however, that my broken foot seems to be making new bone nicely. As far as side effects, I do notice that on the days that I take it (once a week) I seem to have more heartburn. I was told to take it first thing in the morning, don’t lay down after, and wait at least one half hour before eating or taking meds. I also take pantoprazole and need to wait after taking that before I eat. I’m glad it’s only once a week.