I take D-Mannose daily. From what I have read, it causes no problems if you are diabetic. I also have started taking a new product I have seen on line and have researched. It is called Utiva - which packs 36mg of PAC's in each capsule. You take 1 a day. I talked to my Mayo urologist and he said that would be beneficial to take and would not cause any problems. Utiva also has a support group on line that helps quite a bit. Hope this helps.